Ontology highlight
ABSTRACT:
SUBMITTER: Li L
PROVIDER: S-EPMC6963241 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Li Li L Chen Han H Marin David D Xi Yuanxin Y Miao Qi Q Lv Jiangxing J Banerjee Pinaki Prosad PP Shaim Hila H Daher May M Basar Rafet R Imahashi Nobuhiko N Jimenez Juan J Hu Bingqian B Mehta Rohtesh S RS Kerbauy Lucila Nassif LN Kaplan Mecit M Mendt Mayela M Ozcan Gonca G Gokdemir Elif E Hernandez Sanabria Mayra M Li Ye Y Chen Ken K Wang Jing J Muniz-Feliciano Luis L Zhao Wei-Li WL Champlin Richard E RE Shpall Elizabeth J EJ Rezvani Katayoun K
Blood advances 20191201 23
Natural killer (NK) cells are highly heterogeneous, with vast phenotypic and functional diversity at the single-cell level. They are involved in the innate immune response against malignant and virus-infected cells. To understand the effect of NK diversity during immune recovery on the antitumor response after cord blood transplantation (CBT), we used high-dimensional mass cytometry and the metrics of NK cell diversity to study the NK cell repertoire in serial samples from 43 CBT recipients. A h ...[more]