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ABSTRACT: Objectives
The risk factors and clinical effect of elevated mitral valve (MV) gradients after valve repair for degenerative valve disease remain insufficiently understood.Methods
Between January 2004 and December 2015, a total of 484 patients underwent valve repair for degenerative disease. A true-sized full annuloplasty ring was implanted in all cases. We analysed the effect of preoperative and intraoperative factors on the postrepair gradient. Additionally, we explored the effect of postrepair gradients on long-term outcomes.Results
On linear regression analysis, postrepair MV gradients were associated with patient age (coefficient?=?-0.110, standard error?=?0.005, P?=?0.034), body surface area (coefficient?=?0.905, standard error?=?0.340, P?=?0.008), implanted annuloplasty ring size (coefficient?=?-0.181, standard error?=?0.018, P?ConclusionsFollowing valve repair for degenerative MV disease, elevated gradients occur even when true-sized annuloplasty is performed. The late clinical results of valve repair with elevated postrepair gradient are impaired and further studies are needed to explore preventive measures aimed at resolving the issue.
SUBMITTER: Tomsic A
PROVIDER: S-EPMC6964229 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Tomšič Anton A Hiemstra Yasmine L YL Arabkhani Bardia B Mertens Bart J A BJA van Brakel Thomas J TJ Versteegh Michel I M MIM Marsan Nina Ajmone NA Klautz Robert J M RJM Palmen Meindert M
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20200201 2
<h4>Objectives</h4>The risk factors and clinical effect of elevated mitral valve (MV) gradients after valve repair for degenerative valve disease remain insufficiently understood.<h4>Methods</h4>Between January 2004 and December 2015, a total of 484 patients underwent valve repair for degenerative disease. A true-sized full annuloplasty ring was implanted in all cases. We analysed the effect of preoperative and intraoperative factors on the postrepair gradient. Additionally, we explored the effe ...[more]