Ontology highlight
ABSTRACT:
SUBMITTER: Buchman A
PROVIDER: S-EPMC6964813 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Buchman Anna A Gamez Stephanie S Li Ming M Antoshechkin Igor I Li Hsing-Han HH Wang Hsin-Wei HW Chen Chun-Hong CH Klein Melissa J MJ Duchemin Jean-Bernard JB Crowe James E JE Paradkar Prasad N PN Akbari Omar S OS
PLoS pathogens 20200116 1
With dengue virus (DENV) becoming endemic in tropical and subtropical regions worldwide, there is a pressing global demand for effective strategies to control the mosquitoes that spread this disease. Recent advances in genetic engineering technologies have made it possible to create mosquitoes with reduced vector competence, limiting their ability to acquire and transmit pathogens. Here we describe the development of Aedes aegypti mosquitoes synthetically engineered to impede vector competence t ...[more]