Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC6965063 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Zhang Yingmiao Y Zhang Song S He Yingxia Y Sun Ziyong Z Cai Wentong W Lv Yin Y Jiang Lingyu L Li Qiao Q Zhu Sizhe S Li Wenjin W Ye Chenglin C Wu Bicong B Xue Ying Y Chen Hongxiang H Cai Huahua H Chen Tie T
Frontiers in cellular and infection microbiology 20200110
Uropathogenic <i>Escherichia coli</i> (UPEC), a Gram-negative bacterial pathogen, is a major causative agent of urinary tract infections (UTIs). However, the molecular mechanisms of how UPEC causes infections have not been determined. Recent studies indicated that certain enteric Gram-negative bacteria interact with and hijack innate immune receptors DC-SIGN (CD209a) and SIGNR1 (CD209b), often expressed by antigen-presenting cells (APCs), such as macrophages, leading to dissemination and infecti ...[more]