The Fungal Pathogen Candida albicans Promotes Bladder Colonization of Group B Streptococcus.
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ABSTRACT:
SUBMITTER: Shing SR
PROVIDER: S-EPMC6966239 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
The Fungal Pathogen <i>Candida albicans</i> Promotes Bladder Colonization of Group B <i>Streptococcus</i>.
Shing Samuel R SR Ramos Anissa R AR Patras Kathryn A KA Riestra Angelica M AM McCabe Sinead S Nizet Victor V Coady Alison A
Frontiers in cellular and infection microbiology 20200110
Group B <i>Streptococcus</i> (GBS) is a common cause of bacterial urinary tract infections (UTI) in susceptible populations, including pregnant women and the elderly. However, the factors that govern GBS persistence and disease severity in this niche are not fully understood. Here, we report that the presence of the fungus <i>Candida albicans</i>, a common urogenital colonizer, can promote GBS UTI. Co-inoculation of GBS with <i>C. albicans</i> increased bacterial adherence to bladder epithelium ...[more]
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