Diversity and Function of Phage Encoded Depolymerases.
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ABSTRACT:
SUBMITTER: Knecht LE
PROVIDER: S-EPMC6966330 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Diversity and Function of Phage Encoded Depolymerases.
Knecht Leandra E LE Veljkovic Marjan M Fieseler Lars L
Frontiers in microbiology 20200110
Bacteriophages of the <i>Podoviridae</i> family often exhibit so-called depolymerases as structural components of the virion. These enzymes appear as tail spike proteins (TSPs). After specific binding to capsular polysaccharides (CPS), exopolysaccharides (EPS) or lipopolysaccharide (LPS) of the host bacteria, polysaccharide-repeating units are specifically cleaved. Finally, the phage reaches the last barrier, the cell wall, injects its DNA, and infects the cell. Recently, similar enzymes from ba ...[more]
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