Ontology highlight
ABSTRACT:
SUBMITTER: Itami-Matsumoto S
PROVIDER: S-EPMC6966514 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Itami-Matsumoto Saori S Hayakawa Michiyo M Uchida-Kobayashi Sawako S Enomoto Masaru M Tamori Akihiro A Mizuno Kazuyuki K Toyoda Hidenori H Tamura Takeyuki T Akutsu Tatsuya T Ochiya Takahiro T Kawada Norifumi N Murakami Yoshiki Y
Biomedicines 20191103 4
Direct-acting antiviral (DAA) therapy for chronic hepatitis C virus (HCV) infection patients (CH) results in a sustained viral response (SVR) in over 95% of patients. However, hepatocellular carcinoma (HCC) occurs in 1-5% of patients who achieved an SVR after treatment with interferon. We attempted to develop a minimally invasive and highly reliable method of predicting the occurrence and recurrence of HCC in patients who achieved an SVR with DAA therapy. The exosomal miRNA expression patterns o ...[more]