Ontology highlight
ABSTRACT:
SUBMITTER: Park JH
PROVIDER: S-EPMC6966701 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Park James H JH van Wyk Hester H McMillan Donald C DC Edwards Joanne J Orange Clare C Horgan Paul G PG Roxburgh Campbell Sd CS
The journal of pathology. Clinical research 20191014 1
The tumour microenvironment (TME) is recognised as an important prognostic characteristic and therapeutic target in patients with colorectal cancer (CRC). However, assessment generally utilises surgically resected specimens, precluding neoadjuvant targeting. The present study investigated the feasibility of intra-epithelial CD3<sup>+</sup> T-lymphocyte density and tumour stroma percentage (TSP) assessment using preoperative colonoscopic biopsies from 115 patients who had undergone resection of s ...[more]