Ontology highlight
ABSTRACT:
SUBMITTER: Aggarwal JA
PROVIDER: S-EPMC6969049 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Scientific reports 20200117 1
Motoneurons are the final output pathway for the brain's influence on behavior. Here we identify properties of hypoglossal motor output to the tongue musculature. Tongue motor control is critical to the pathogenesis of obstructive sleep apnea, a common and serious sleep-related breathing disorder. Studies were performed on mice expressing a light sensitive cation channel exclusively on cholinergic neurons (ChAT-ChR2(H134R)-EYFP). Discrete photostimulations under isoflurane-induced anesthesia fro ...[more]