Ontology highlight
ABSTRACT:
SUBMITTER: Hagihara M
PROVIDER: S-EPMC6970176 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Hagihara Mao M Kuroki Yasutoshi Y Ariyoshi Tadashi T Higashi Seiya S Fukuda Kazuo K Yamashita Rieko R Matsumoto Asami A Mori Takeshi T Mimura Kaoru K Yamaguchi Naoko N Okada Shoshiro S Nonogaki Tsunemasa T Ogawa Tadashi T Iwasaki Kenta K Tomono Susumu S Asai Nobuhiro N Koizumi Yusuke Y Oka Kentaro K Yamagishi Yuka Y Takahashi Motomichi M Mikamo Hiroshige H
iScience 20191213 1
Clostridium butyricum MIYAIRI 588 (CBM 588) is a probiotic bacterium that has previously been used to prevent antibiotic-associated diarrhea. However, the underlying mechanism by which CBM 588 protects the gut epithelial barrier remains unclear. Here, we show that CBM 588 increased the abundance of Bifidobacterium, Lactobacillus, and Lactococcus species in the gut microbiome and also enhanced the intestinal barrier function of mice with antibiotic-induced dysbiosis. Additionally, CBM 588 signifi ...[more]