Ontology highlight
ABSTRACT:
SUBMITTER: Warnau J
PROVIDER: S-EPMC6970264 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Warnau Judith J Wöhlert David D Okazaki Kei-Ichi KI Yildiz Özkan Ö Gamiz-Hernandez Ana P AP Kaila Ville R I VRI Kühlbrandt Werner W Hummer Gerhard G
The journal of physical chemistry. B 20200102 2
Cells employ membrane-embedded antiporter proteins to control their pH, salt concentration, and volume. The large family of cation/proton antiporters is dominated by Na<sup>+</sup>/H<sup>+</sup> antiporters that exchange sodium ions against protons, but homologous K<sup>+</sup>/H<sup>+</sup> exchangers have recently been characterized. We show experimentally that the electroneutral antiporter NhaP1 of <i>Methanocaldococcus jannaschii</i> (MjNhaP1) is highly selective for Na<sup>+</sup> ions. We ...[more]