Ontology highlight
ABSTRACT:
SUBMITTER: Shi S
PROVIDER: S-EPMC6971263 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Shi Shan S Ma Ke K Bin Na-Ryum NR Harada Hidekiyo H Xie Xiaoyu X Huang Mengjia M Liu Haiyu H Lee Soomin S Wang Xue Fan XF Adachi Roberto R Monnier Philippe P PP Zhang Liang L Sugita Shuzo S
Scientific reports 20200120 1
Recent evidence suggests that SNARE fusion machinery play critical roles in postsynaptic neurotransmitter receptor trafficking, which is essential for synaptic plasticity. However, the key SNAREs involved remain highly controversial; syntaxin-3 and syntaxin-4 are leading candidates for the syntaxin isoform underlying postsynaptic plasticity. In a previous study, we showed that pyramidal-neuron specific conditional knockout (cKO) of syntaxin-4 significantly reduces basal transmission, synaptic pl ...[more]