Dataset Information
Mild, Selective Ru-Catalyzed Deuteration Using D2 O as a Deuterium Source.
Ontology highlight
ABSTRACT:
SUBMITTER: Eisele P
PROVIDER: S-EPMC6972544 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Publications
Mild, Selective Ru-Catalyzed Deuteration Using D<sub>2</sub> O as a Deuterium Source.
Chemistry (Weinheim an der Bergstrasse, Germany) 20191128 72
A method for the selective deuteration of polyfunctional organic molecules using catalytic amounts of [RuCl<sub>2</sub> (PPh<sub>3</sub> )<sub>3</sub> ] and D<sub>2</sub> O as a deuterium source is presented. Through variation of additives like CuI, KOH, and various amounts of zinc powder, orthogonal chemoselectivities in the deuteration process are observed. Mechanistic investigation indicates the presence of different, defined Ru-complexes under the given specific conditions. ...[more]