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ABSTRACT:
SUBMITTER: Feyereisen M
PROVIDER: S-EPMC6974642 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Applied and environmental microbiology 20200121 3
<i>Lactobacillus brevis</i> beer-spoiling strains harbor plasmids that contain genes such as <i>horA</i>, <i>horC</i>, and <i>hitA</i> which are known to confer hop tolerance. The <i>L. brevis</i> beer-spoiling strain UCCLBBS124, which possesses four plasmids, was treated with novobiocin, resulting in the isolation of UCCLBBS124 derivatives exhibiting hop sensitivity and an inability to grow in beer. One selected derivative was shown to have lost a single plasmid, here designated UCCLBBS124_D, w ...[more]