Browse
Submit Data
Databases
API
Help

Dataset Information

17 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Boosting Ethylene/Ethane Separation within Copper(I)-Chelated Metal-Organic Frameworks through Tailor-Made Aperture and Specific π-Complexation.

ABSTRACT: The development of new materials for separating ethylene (C2H4) from ethane (C2H6) by adsorption is of great importance in the petrochemical industry, but remains very challenging owing to their close molecular sizes and physical properties. Using isoreticular chemistry in metal-organic frameworks (MOFs) enables the precise design and construction of target materials with suitable aperture sizes and functional sites for gas separations. Herein, it is described that fine-tuning of pore size and π-complexation simultaneously in microporous copper(I)-chelated MOFs can remarkably boost the C2H4/C2H6 adsorption selectivity. The judicious choice of organic linkers with a different number of carboxyl groups in the UiO-66 framework not only allows the fine tuning of the pore size but also immobilizes copper(I) ions onto the framework. The tailor-made adsorbent, CuI@UiO-66-(COOH)2, thus possesses the optimal pore window size and chelated Cu(I) ions to form π-complexation with C2H4 molecules. It can rapidly adsorb C2H4 driven by the strong π-complexation interactions, while effectively reducing C2H6 uptake due to the selective size-sieving. Therefore, this material exhibits an ultrahigh C2H4/C2H6 selectivity (80.8), outperforming most previously described benchmark materials. The exceptional separation performance of CuI@UiO-66-(COOH)2 is validated by breakthrough experiments for 50/50 v/v C2H4/C2H6 mixtures under ambient conditions.

SUBMITTER: Zhang L

PROVIDER: S-EPMC6974952 | biostudies-literature |

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Similar Datasets

Pillar-layer Zn-triazolate-dicarboxylate frameworks with a customized pore structure for efficient ethylene purification from ethylene/ethane/acetylene ternary mixtures.

Project description:The selective adsorption of C2H6 and C2H2 over C2H4 from C2H2/C2H4/C2H6 ternary mixtures for one-step C2H4 purification represents a crucial yet challenging task in industry. The pore structure of the adsorbents must be finely tailored to meet the demanding requirements for the separation considering the very similar physicochemical properties of the three gases. Herein, we report a Zn-triazolate-dicarboxylate framework, HIAM-210, featuring a novel topology which possesses one-dimensional channels decorated with adjacent uncoordinated carboxylate-O atoms. The suitable pore size and customized pore environment enable the compound to selectively capture C2H6 and C2H2 with high C2H2/C2H4 and C2H6/C2H4 selectivities of both 2.0. Breakthrough experiments show that polymer-grade C2H4 can be directly harvested from C2H2/C2H4/C2H6 (34/33/33 and 1/90/9) ternary mixtures. The underlying mechanism of the preferential adsorption was uncovered by grand canonical Monte Carlo simulations and DFT calculations.

| S-EPMC10246669 | biostudies-literature

Site-Selective Acylations with Tailor-Made Catalysts.

Project description:The acylation of alcohols catalyzed by N,N-dimethylamino pyridine (DMAP) is, despite its widespread use, sometimes confronted with substrate-specific problems: For example, target compounds with multiple hydroxy groups may show insufficient selectivity for one hydroxyl, and the resulting product mixtures are hardly separable. Here we describe a concept that aims at tailor-made catalysts for the site-specific acylation. To this end, we introduce a catalyst library where each entry is constructed by connecting a variable and readily tuned peptide scaffold with a catalytically active unit based on DMAP. For selected examples, we demonstrate how library screening leads to the identification of optimized catalysts, and the substrates of interest can be converted with a markedly enhanced site-selectivity compared with only DMAP. Furthermore, substrate-optimized catalysts of this type can be used to selectively convert "their" substrate in the presence of structurally similar compounds, an important requisite for reactions with mixtures of substances.

| S-EPMC5069569 | biostudies-literature

Intermolecular π-π Stacking Interactions Made Visible.

Project description:Mixing the liquids hexafluorobenzene (1) and 1,3,5-trimethylbenzene (mesitylene, 2) results in a crystalline solid with a melting point of 34 °C. The solid consists of alternating π-π stacked pillars of both aromatics. This simple experiment can be used to visually demonstrate the existence and the effect of noncovalent intermolecular π-π stacking interactions. Both benzene derivatives are relatively benign and widely available, and the experiment can be performed within minutes for less than $15 when done on a 22 mL scale (total volume). The demonstration is very robust, as 1:2 mixtures in volume ratios between 2/3 and 3/2 all give a visually similar result (molar ratios of 1.8-0.8). Substituting 2 with the liquid aromatics o-xylene, p-xylene, and aniline also resulted in the formation of a crystalline solid, while using many other liquid aromatics did not.

| S-EPMC7876799 | biostudies-literature

Zinc Finger Nucleases: Tailor-made for Gene Therapy.

Project description:Genome editing with the use of zinc finger nucleases has been successfully applied to variety of a eukaryotic cells. Furthermore, the proof of concept for this approach has been extended to diverse animal models from Drosophila to mice. Engineered zinc finger nucleases are able to target specifically and manipulate disease-causing genes through site-specific double strand DNA breaks followed by non-homologous end joining or homologous recombination mechanisms. Consequently, this technology has considerable flexibility that can result in either a gain or loss of function of the targeted gene. In addition to this flexibility, gene therapy by zinc finger nucleases may enable persistent long term gene modification without continuous transfection- a potential advantage over RNA interference or direct gene inhibitors. With systemic viral delivery systems, this gene-editing approach corrected the mutant factor IX in models of mouse hemophilia. Moreover, phase I clinical trials have been initiated with zinc finger nucleases in patients with glioblastoma and HIV. Thus, this emerging field has significant promise as a therapeutic strategy for human genetic diseases, infectious diseases and oncology. In this article, we will review recent advances and potential risks in zinc finger nuclease gene therapy.

| S-EPMC3801298 | biostudies-literature

Molecular Sieving of Ethane from Ethylene through the Molecular Cross-Section Size Differentiation in Gallate-based Metal-Organic Frameworks.

Project description:Purification of C2 H4 from an C2 H4 /C2 H6 mixture, one of the most important while challenging industrial separation processes, is mainly through energy-intensive cryogenic distillation. Now a family of gallate-based metal-organic framework (MOF) materials is presented, M-gallate (M=Ni, Mg, Co), featuring 3D interconnected zigzag channels, the aperture sizes of which (3.47-3.69 Å) are ideally suitable for molecular sieving of ethylene (3.28×4.18×4.84 Å3 ) and ethane (3.81×4.08×4.82 Å3 ) through molecular cross-section size differentiation. Co-gallate shows an unprecedented IAST selectivity of 52 for C2 H4 over C2 H6 with a C2 H4 uptake of 3.37 mmol g-1 at 298 K and 1 bar, outperforming the state-of-the-art MOF material NOTT-300. Direct breakthrough experiments with equimolar C2 H4 /C2 H6 mixtures confirmed that M-gallate is highly selective for ethylene. The adsorption structure and mechanism of ethylene in the M-gallate was further studied through neutron diffraction experiments.

| S-EPMC7954079 | biostudies-literature

Tailor-made temperature-dependent thermal conductivity via interparticle constriction.

Project description:Managing heat is a major challenge to meet future demands for a sustainable use of our energy resources. This requires materials, which can be custom-designed to exhibit specific temperature-dependent thermal transport properties to become integrated into thermal switches, transistors, or diodes. Common crystalline and amorphous materials are not suitable, owing to their gradual changes of the temperature-dependent thermal conductivity. We show how a second-order phase transition fully controls the temperature-dependent thermal transport properties of polymer materials. We demonstrate four major concepts based on a colloidal superstructure: (i) control of transition temperature, (ii) width of phase transition regime, (iii) multistep transitions, and (iv) step height of the transition. Most importantly, this unique control over thermal conductivity is only governed by the interparticle constriction, the particle composition, and its mesostructure. Our concept is therefore also applicable to a wide variety of other particulate materials.

| S-EPMC5693563 | biostudies-literature

Molecular Scissors for Tailor-Made Modification of Siloxane Scaffolds.

Project description:The controlled design of functional oligosiloxanes is an important topic in current research. A consecutive Si-O-Si bond cleavage/formation using siloxanes that are substituted with 1,2-diaminobenzene derivatives acting as molecular scissors is presented. The method allows to cut at certain positions of a siloxane scaffold forming a cyclic diaminosilane or -siloxane intermediate and then to introduce new functional siloxy units. The procedure could be extended to a direct one-step cleavage of chlorooligosiloxanes. Both siloxane formation and cleavage proceed with good to excellent yields, high regioselectivity, and great variability of the siloxy units. Control of the selectivity is achieved by the choice of the amino substituent. Insight into the mechanism was provided by low temperature NMR studies and the isolation of a lithiated intermediate.

| S-EPMC9299477 | biostudies-literature

Tailor-made porosities of fluorene-based porous organic frameworks for the pre-designable fabrication of palladium nanoparticles with size, location and distribution control.

Project description:Porous organic frameworks (POFs) are a promising new class of support for metal nanoparticles (NPs), with the size, location and distribution of metal NPs are closely related to the porous nature of the POFs. In this contribution, three fluorene-based POFs containing coordination-inert hydrogen, propyl and benzyl substituents at the 9-position of the fluorene units (POF-1, POF-2 and POF-3) were synthesized through a simple click reaction. The substituents exerted important influences on the surface area, pore volume and pore size of the POFs. Palladium NPs with a pre-designable size, location and distribution were synthesized through a substituent-controlled strategy. When POF-1 was employed as a support, ultrafine palladium NPs in the interior pores were generated, while the introduction of propyl at the 9-position of fluorene in POF-2 gave rise to dual-distributed palladium NPs in the interior pores and on the external surface. The use of the bulkier benzyl substituent resulted in the formation of palladium NPs on the external surface of POF-3. The hydrogenation of olefins has demonstrated that palladium NPs on the external surface possessed higher catalytic activity, while palladium NPs in the interior pores exhibited higher stability and recyclability. In addition, after Pd/POF-1, Pd/POF-2 and Pd/POF-3 were stored in air over half a year, palladium NPs in the interior pores showed a negligible change in comparison with fresh samples, while an obvious agglomeration was observed for palladium NPs on the external surface.

| S-EPMC5975943 | biostudies-literature

Metal-organic frameworks tailor the properties of aluminum nanocrystals.

Project description:Metal-organic frameworks (MOFs) and metal nanoparticles are two classes of materials that have received considerable recent attention, each for controlling chemical reactivities, albeit in very different ways. Here, we report the growth of MOF shell layers surrounding aluminum nanocrystals (Al NCs), an Earth-abundant metal with energetic, plasmonic, and photocatalytic properties. The MOF shell growth proceeds by means of dissolution-and-growth chemistry that uses the intrinsic surface oxide of the NC to obtain the Al3+ ions accommodated into the MOF nodes. Changes in the Al NC plasmon resonance provide an intrinsic optical probe of its dissolution and growth kinetics. This same chemistry enables a highly controlled oxidation of the Al NCs, providing a precise method for reducing NC size in a shape-preserving manner. The MOF shell encapsulation of the Al NCs results in increased efficiencies for plasmon-enhanced photocatalysis, which is observed for the hydrogen-deuterium exchange and reverse water-gas shift reactions.

| S-EPMC6368424 | biostudies-literature

Tailor-made RNAi knockdown against triplet repeat disease-causing alleles.

Project description:Nucleotide variations, including SNPs, in the coding regions of disease genes are important targets for RNAi treatment, which is a promising medical treatment for intractable diseases such as triplet repeat diseases. However, the identification of such nucleotide variations and the design of siRNAs conferring disease allele-specific RNAi are quite difficult. In this study we developed a pull-down method to rapidly identify coding SNP (cSNP) haplotypes of triple repeat, disease-causing alleles, and we demonstrated disease allele-specific RNAi that targeted cSNP sites in mutant Huntingtin alleles, each of which possessed a different cSNP haplotype. Therefore, the methods presented here allow for allele-specific RNAi knockdown against disease-causing alleles by using siRNAs specific to disease-linked cSNP haplotypes, and advanced progress toward tailor-made RNAi treatments for triplet repeat diseases.

| S-EPMC3003091 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data