Ontology highlight
ABSTRACT:
SUBMITTER: Strawbridge RJ
PROVIDER: S-EPMC6975521 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Strawbridge Rona J RJ Ward Joey J Bailey Mark E S MES Cullen Breda B Ferguson Amy A Graham Nicholas N Johnston Keira J A KJA Lyall Laura M LM Pearsall Robert R Pell Jill J Shaw Richard J RJ Tank Rachana R Lyall Donald M DM Smith Daniel J DJ
Arteriosclerosis, thrombosis, and vascular biology 20191205 2
<h4>Objective</h4>Atherosclerosis is the underlying cause of most cardiovascular disease, but mechanisms underlying atherosclerosis are incompletely understood. Ultrasound measurement of the carotid intima-media thickness (cIMT) can be used to measure vascular remodeling, which is indicative of atherosclerosis. Genome-wide association studies have identified many genetic loci associated with cIMT, but heterogeneity of measurements collected by many small cohorts have been a major limitation in t ...[more]