Dataset Information

Algorithmic handwriting analysis of the Samaria inscriptions illuminates bureaucratic apparatus in biblical Israel.

ABSTRACT: Past excavations in Samaria, capital of biblical Israel, yielded a corpus of Hebrew ink on clay inscriptions (ostraca) that documents wine and oil shipments to the palace from surrounding localities. Many questions regarding these early 8th century BCE texts, in particular the location of their composition, have been debated. Authorship in countryside villages or estates would attest to widespread literacy in a relatively early phase of ancient Israel's history. Here we report an algorithmic investigation of 31 of the inscriptions. Our study establishes that they were most likely written by two scribes who recorded the shipments in Samaria. We achieved our results through a method comprised of image processing and newly developed statistical learning techniques. These outcomes contrast with our previous results, which indicated widespread literacy in the kingdom of Judah a century and half to two centuries later, ca. 600 BCE.

SUBMITTER: Faigenbaum-Golovin S

PROVIDER: S-EPMC6975535 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Algorithmic handwriting analysis of the Samaria inscriptions illuminates bureaucratic apparatus in biblical Israel.

Faigenbaum-Golovin Shira S Shaus Arie A Sober Barak B Turkel Eli E Piasetzky Eli E Finkelstein Israel I

PloS one 20200122 1

Past excavations in Samaria, capital of biblical Israel, yielded a corpus of Hebrew ink on clay inscriptions (ostraca) that documents wine and oil shipments to the palace from surrounding localities. Many questions regarding these early 8th century BCE texts, in particular the location of their composition, have been debated. Authorship in countryside villages or estates would attest to widespread literacy in a relatively early phase of ancient Israel's history. Here we report an algorithmic inv ...[more]

PMID: 31968002

Similar Datasets

Project description:The apicomplexan parasites Plasmodium spp. are the causative agents of malaria, a disease that poses a significant global health burden. Plasmodium spp. initiate infection of the human host by transforming and replicating within hepatocytes. This liver stage (LS) is poorly understood compared to other Plasmodium life stages, which has hindered our ability to target these parasites for disease prevention. We conducted an extensive transcriptome sequencing (RNA-Seq) analysis throughout the Plasmodium berghei LS, covering as early as 2?h postinfection (hpi) and extending to 48 hpi. Our data revealed that hundreds of genes are differentially expressed at 2 hpi and that multiple genes shown to be important for later infection are upregulated as early as 12 hpi. Using hierarchical clustering along with coexpression analysis, we identified clusters functionally enriched for important liver-stage processes such as interactions with the host cell and redox homeostasis. Furthermore, some of these clusters were highly correlated to the expression of ApiAP2 transcription factors, while showing enrichment of mostly uncharacterized DNA binding motifs. This finding indicates potential LS targets for these transcription factors, while also hinting at alternative uncharacterized DNA binding motifs and transcription factors during this stage. Our work presents a window into the previously undescribed transcriptome of Plasmodium upon host hepatocyte infection to enable a comprehensive view of the parasite's LS. These findings also provide a blueprint for future studies that extend hypotheses concerning LS gene function in P. berghei to human-infective Plasmodium parasites.IMPORTANCE The LS of Plasmodium infection is an asymptomatic yet necessary stage for producing blood-infective parasites, the causative agents of malaria. Blocking the liver stage of the life cycle can prevent clinical malaria, but relatively less is known about the parasite's biology at this stage. Using the rodent model P. berghei, we investigated whole-transcriptome changes occurring as early as 2 hpi of hepatocytes. The transcriptional profiles of early time points (2, 4, 12, and 18 hpi) have not been accessible before due to the technical challenges associated with liver-stage infections. Our data now provide insights into these early parasite fluxes that may facilitate establishment of infection, transformation, and replication in the liver.

Dataset Information

Algorithmic handwriting analysis of the Samaria inscriptions illuminates bureaucratic apparatus in biblical Israel.

Publications

Algorithmic handwriting analysis of the Samaria inscriptions illuminates bureaucratic apparatus in biblical Israel.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets