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Endometrial preparation for frozen-thawed embryo transfer in an artificial cycle: transdermal versus vaginal estrogen.

ABSTRACT: The objective was to compare the endometrial thickness (ET) in a frozen embryo transfer (FET) cycle between transdermal and vaginal estrogen. Our secondary objectives were to compare the patient satisfaction and the pregnancy outcomes. Prospective monocentric cohort study between 01/2017 and 12/2017 at a single institution. Choice of administration was left to the patient. 119 cycles had transdermal estrogen (T-group) and 199 had vaginal estrogen (V-group). The ET at 10?±?1 days of treatment was significantly higher in the T-group compared to the V-group (9.9 vs 9.3?mm, p?=?0.03). In the T-group, the mean duration of treatment was shorter (13.6 vs 15.5 days, p?

SUBMITTER: Corroenne R 

PROVIDER: S-EPMC6976623 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Endometrial preparation for frozen-thawed embryo transfer in an artificial cycle: transdermal versus vaginal estrogen.

Corroenne Romain R   El Hachem Hady H   Verhaeghe Caroline C   Legendre Guillaume G   Dreux Cecile C   Jeanneteau Pauline P   Descamps Philippe P   May-Panloup Pascale P   Bouet Pierre-Emmanuel PE  

Scientific reports 20200122 1

The objective was to compare the endometrial thickness (ET) in a frozen embryo transfer (FET) cycle between transdermal and vaginal estrogen. Our secondary objectives were to compare the patient satisfaction and the pregnancy outcomes. Prospective monocentric cohort study between 01/2017 and 12/2017 at a single institution. Choice of administration was left to the patient. 119 cycles had transdermal estrogen (T-group) and 199 had vaginal estrogen (V-group). The ET at 10 ± 1 days of treatment was  ...[more]