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Gene content evolution in the arthropods.


ABSTRACT: BACKGROUND:Arthropods comprise the largest and most diverse phylum on Earth and play vital roles in nearly every ecosystem. Their diversity stems in part from variations on a conserved body plan, resulting from and recorded in adaptive changes in the genome. Dissection of the genomic record of sequence change enables broad questions regarding genome evolution to be addressed, even across hyper-diverse taxa within arthropods. RESULTS:Using 76 whole genome sequences representing 21 orders spanning more than 500 million years of arthropod evolution, we document changes in gene and protein domain content and provide temporal and phylogenetic context for interpreting these innovations. We identify many novel gene families that arose early in the evolution of arthropods and during the diversification of insects into modern orders. We reveal unexpected variation in patterns of DNA methylation across arthropods and examples of gene family and protein domain evolution coincident with the appearance of notable phenotypic and physiological adaptations such as flight, metamorphosis, sociality, and chemoperception. CONCLUSIONS:These analyses demonstrate how large-scale comparative genomics can provide broad new insights into the genotype to phenotype map and generate testable hypotheses about the evolution of animal diversity.

SUBMITTER: Thomas GWC 

PROVIDER: S-EPMC6977273 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Gene content evolution in the arthropods.

Thomas Gregg W C GWC   Dohmen Elias E   Hughes Daniel S T DST   Murali Shwetha C SC   Poelchau Monica M   Glastad Karl K   Anstead Clare A CA   Ayoub Nadia A NA   Batterham Phillip P   Bellair Michelle M   Binford Greta J GJ   Chao Hsu H   Chen Yolanda H YH   Childers Christopher C   Dinh Huyen H   Doddapaneni Harsha Vardhan HV   Duan Jian J JJ   Dugan Shannon S   Esposito Lauren A LA   Friedrich Markus M   Garb Jessica J   Gasser Robin B RB   Goodisman Michael A D MAD   Gundersen-Rindal Dawn E DE   Han Yi Y   Handler Alfred M AM   Hatakeyama Masatsugu M   Hering Lars L   Hunter Wayne B WB   Ioannidis Panagiotis P   Jayaseelan Joy C JC   Kalra Divya D   Khila Abderrahman A   Korhonen Pasi K PK   Lee Carol Eunmi CE   Lee Sandra L SL   Li Yiyuan Y   Lindsey Amelia R I ARI   Mayer Georg G   McGregor Alistair P AP   McKenna Duane D DD   Misof Bernhard B   Munidasa Mala M   Munoz-Torres Monica M   Muzny Donna M DM   Niehuis Oliver O   Osuji-Lacy Nkechinyere N   Palli Subba R SR   Panfilio Kristen A KA   Pechmann Matthias M   Perry Trent T   Peters Ralph S RS   Poynton Helen C HC   Prpic Nikola-Michael NM   Qu Jiaxin J   Rotenberg Dorith D   Schal Coby C   Schoville Sean D SD   Scully Erin D ED   Skinner Evette E   Sloan Daniel B DB   Stouthamer Richard R   Strand Michael R MR   Szucsich Nikolaus U NU   Wijeratne Asela A   Young Neil D ND   Zattara Eduardo E EE   Benoit Joshua B JB   Zdobnov Evgeny M EM   Pfrender Michael E ME   Hackett Kevin J KJ   Werren John H JH   Worley Kim C KC   Gibbs Richard A RA   Chipman Ariel D AD   Waterhouse Robert M RM   Bornberg-Bauer Erich E   Hahn Matthew W MW   Richards Stephen S  

Genome biology 20200123 1


<h4>Background</h4>Arthropods comprise the largest and most diverse phylum on Earth and play vital roles in nearly every ecosystem. Their diversity stems in part from variations on a conserved body plan, resulting from and recorded in adaptive changes in the genome. Dissection of the genomic record of sequence change enables broad questions regarding genome evolution to be addressed, even across hyper-diverse taxa within arthropods.<h4>Results</h4>Using 76 whole genome sequences representing 21  ...[more]

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