Ontology highlight
ABSTRACT:
SUBMITTER: Hasnain MJU
PROVIDER: S-EPMC6977751 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Hasnain Mirza Jawad Ul MJU Shoaib Muhammad M Qadri Salman S Afzal Bakhtawar B Anwar Tehreem T Abbas Syed Hassan SH Abbas Syed Hassan SH Sarwar Amina A Talha Malik Hafiz Muhammad HM Tariq Pervez Muhammad M
PloS one 20200123 1
Single Nucleotide Polymorphisms (SNPs) are the most common candidate mutations in human beings that play a vital role in the genetic basis of certain diseases. Previous studies revealed that Solute Carrier Family 26 Member 4 (SLC26A4) being an essential gene of the multi-faceted transporter family SLC26 facilitates reflexive movement of Iodide into follicular lumen through apical membrane of thyrocyte. SLC26A4 gene encodes Pendred protein, a membrane glycoprotein, highly hydrophobic in nature, p ...[more]