Dataset Information

Advances in diagnostic applications for monitoring intraocular pressure in Glaucoma: A review.

ABSTRACT: Continuous intraocular pressure (IOP) monitoring for improving glaucoma diagnosis and treatment has remained a challenge for the past 60 years because glaucoma is the second leading cause of irreversible blindness worldwide. Several devices with different measurement principles and recently developed biosensors with semiconductor materials offer exciting properties. However, none of these devices for continuous IOP monitoring have been fully integrated into clinical practice, primarily due to technical problems. This review summarizes state-of-the-art biosensors developed for IOP monitoring by explaining their basic functions and applications, the main technology (pressure transductors, piezoresistive sensors, capacitive sensors, and resonant sensors), measurement approach (noninvasive, minimally invasive or invasive (surgically implantable)), and telemetry characteristics. To provide updated information for clinicians and researchers, we also describe the advantages and limitations of the application of these new sensors to eye care management. Despite significant improvements in IOP biosensor technology, the accuracy of their measurements must be improved to obtain a clear equivalence with actual IOP (measured in units of mmHg) to facilitate their clinical application. In addition, telemetry systems may be simplified to prevent adverse outcomes for patients and to guarantee the safety of stored data.

SUBMITTER: Sanchez I

PROVIDER: S-EPMC6978552 | biostudies-literature | 2019 Oct - Dec

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Advances in diagnostic applications for monitoring intraocular pressure in Glaucoma: A review.

Sanchez Irene I Martin Raul R

Journal of optometry 20190810 4

Continuous intraocular pressure (IOP) monitoring for improving glaucoma diagnosis and treatment has remained a challenge for the past 60 years because glaucoma is the second leading cause of irreversible blindness worldwide. Several devices with different measurement principles and recently developed biosensors with semiconductor materials offer exciting properties. However, none of these devices for continuous IOP monitoring have been fully integrated into clinical practice, primarily due to te ...[more]

PMID: 31405810

Similar Datasets

Project description:ImportanceThe ability of patients to measure their own intraocular pressure (IOP) would allow more frequent measurements and better appreciation of peak IOP and IOP fluctuation.ObjectiveTo examine whether patients with glaucoma can perform self-tonometry using a rebound tonometer and examine patient acceptability.Design, setting, and participantsAn observational study in which IOP was assessed using Goldmann applanation tonometry and a rebound tonometer. Consecutive patients were provided with a patient information sheet and those consenting to take part in the study received standardized self-tonometry training and were then instructed to measure their own IOP under observation. This study was conducted at a glaucoma clinic at a university hospital from March 1, 2016, to December 30, 2016, and included both eyes of 100 patients with glaucoma or ocular hypertension.Main outcomes and measuresThe percentage of patients who could successfully perform self-tonometry. Complete success was defined by a good technique and an IOP reading within 5 mm Hg of that obtained by a clinician using the same device. A 3-item questionnaire was used to examine perceptions of self-tonometry among patients.ResultsAmong the 100 patients, the mean (SD) age was 67.5 (10.9) years (53% female). A total 73 of 100 patients (73%) met the complete success criteria. An additional 6 patients could use the device but had IOP readings greater than 5 mm Hg different from those obtained by the clinician. On average, IOP by the rebound tonometer was 2.66 mm Hg lower than Goldmann applanation tonometry (95% limits of agreement, -3.48 to 8.80 mm Hg). The IOPs with the rebound tonometer were similar whether obtained by self-tonometry or investigator, with excellent reproducibility with an intraclass correlation coefficient of 0.903 (95% CI, 0.867-0.928). A total of 56 of 79 successful or partially successful patients (71%) felt self-tonometry was easy, with 73 of 79 (92%) reporting self-tonometry to be comfortable, and a similar number happy to perform self-tonometry in the future.Conclusions and relevanceMost patients could perform self-tonometry and the method was acceptable to patients. Self-tonometry has the potential to improve patient engagement, while also providing a more complete picture of IOP changes over time.

Dataset Information

Advances in diagnostic applications for monitoring intraocular pressure in Glaucoma: A review.

Publications

Advances in diagnostic applications for monitoring intraocular pressure in Glaucoma: A review.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets