Discovery of novel plasma biomarker ratios to discriminate traumatic brain injury.
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ABSTRACT:
SUBMITTER: Chen M
PROVIDER: S-EPMC6979479 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Discovery of novel plasma biomarker ratios to discriminate traumatic brain injury.
Chen Michelle M Soosaipillai Antoninus A Fraser Douglas D DD Diamandis Eleftherios P EP
F1000Research 20190927
<b>Background:</b> Traumatic brain injury (TBI) is a major cause of death and disability. Despite increased awareness, reliable biomarkers are urgently needed to aid in all forms of traumatic brain injury diagnosis and prognosis. <b>Methods:</b> Here, we aim to assess the diagnostic utility of known and novel TBI biomarkers in a pilot patient cohort of severe TBI (sTBI) patients and healthy controls. We analyzed concentrations of S100 calcium binding protein B (S100B), neuron specific enolase (N ...[more]
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