Ontology highlight
ABSTRACT:
SUBMITTER: Melamed S
PROVIDER: S-EPMC6980735 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Melamed Sahar S Adams Philip P PP Zhang Aixia A Zhang Hongen H Storz Gisela G
Molecular cell 20191121 2
Base pairing RNAs modulate gene expression in all studied organisms. In many bacteria, the base pairing between most small regulatory RNAs (sRNAs) and their targets is mediated by the Hfq RNA chaperone. However, recent studies have shown FinO-domain proteins also bind sRNAs. To examine the global contribution of the FinO-domain ProQ protein in Escherichia coli, we carried out RIL-seq to identify RNA pairs bound to this protein. The RNA-RNA interactome for ProQ contains hundreds of pairs. Intrigu ...[more]