Ontology highlight
ABSTRACT:
SUBMITTER: Bethke JH
PROVIDER: S-EPMC6981087 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Science advances 20200124 4
Plasmids are key vehicles of horizontal gene transfer (HGT), mobilizing antibiotic resistance, virulence, and other traits among bacterial populations. The environmental and genetic forces that drive plasmid transfer are poorly understood, however, due to the lack of definitive quantification coupled with genomic analysis. Here, we integrate conjugative phenotype with plasmid genotype to provide quantitative analysis of HGT in clinical <i>Escherichia coli</i> pathogens. We find a substantial pro ...[more]