Ontology highlight
ABSTRACT:
SUBMITTER: Ponce-Gallegos MA
PROVIDER: S-EPMC6982076 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Ponce-Gallegos Marco Antonio MA Pérez-Rubio Gloria G García-Carmona Adriana A García-Gómez Jesús J Hernández-Zenteno Rafael R Ramírez-Venegas Alejandra A Falfán-Valencia Ramcés R
International journal of molecular sciences 20191227 1
Protease inhibitor S (PiS) and protease inhibitor Z (PiZ) variants in the <i>SERPINA1</i> gene are the main genetics factors associated with COPD; however, investigations about other polymorphisms are scanty. The aim of this study was to evaluate two missense single nucleotide polymorphisms (SNPs) (rs709932 and rs1303) in the <i>SERPINA1</i> gene in Mexican mestizo patients with chronic obstructive pulmonary disease (COPD) related to tobacco smoking and biomass-burning exposure. 1700 subjects we ...[more]