Ontology highlight
ABSTRACT:
SUBMITTER: Nemeth AM
PROVIDER: S-EPMC6982545 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
ChemMedChem 20191204 2
Infections caused by multidrug-resistant (MDR) bacteria, particularly Gram-negative bacteria, are an escalating global health threat. Often clinicians are forced to administer the last-resort antibiotic colistin; however, colistin resistance is becoming increasingly prevalent, giving rise to the potential for a situation in which there are no treatment options for MDR Gram-negative infections. The development of adjuvants that circumvent bacterial resistance mechanisms is a promising orthogonal ...[more]