The Significance of Sidedness in Patients with Metastatic Colorectal Cancer Treated with Triplet First-line Chemotherapy.

ABSTRACT: BACKGROUND:Recent data have shown that right-sided colon cancer carries poorer prognosis compared to left-sided tumors. This study was aimed to evaluate the progression-free survival, overall survival of patients with metastatic colon cancer of right-sided versus left-sided primaries treated with triplet chemotherapy regimen. METHODS:The medical records of patients with metastatic colorectal cancer treated on phase I-II trial of combination Irinotecan, oxaliplatin, capecitabine, and bevacizumab were reviewed for sidedness of the primary. The analysis was performed for progression-free survival and overall survival according to the sidedness and other known prognostic factors. RESULTS:Out of 53 patients treated with triplet therapy, 11 had right sided and 42 had left-sided primaries. The me

SUBMITTER: Bazarbashi S 

PROVIDER: S-EPMC6982651 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature