Ontology highlight
ABSTRACT:
SUBMITTER: Wang PH
PROVIDER: S-EPMC6983444 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Wang Po-Hsiang PH Chen Yi-Lung YL Wei Sean Ting-Shyang ST Wu Kan K Lee Tzong-Huei TH Wu Tien-Yu TY Chiang Yin-Ru YR
Proceedings of the National Academy of Sciences of the United States of America 20191217 3
Steroid estrogens modulate physiology and development of vertebrates. Conversion of C<sub>19</sub> androgens into C<sub>18</sub> estrogens is thought to be an irreversible reaction. Here, we report a denitrifying <i>Denitratisoma</i> sp. strain DHT3 capable of catabolizing estrogens or androgens anaerobically. Strain DHT3 genome contains a polycistronic gene cluster, <i>emtABCD</i>, differentially transcribed under estrogen-fed conditions and predicted to encode a cobalamin-dependent methyltrans ...[more]