Ontology highlight
ABSTRACT:
SUBMITTER: Tomczyk S
PROVIDER: S-EPMC6983715 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Tomczyk Szymon S Suknovic Nenad N Schenkelaars Quentin Q Wenger Yvan Y Ekundayo Kazadi K Buzgariu Wanda W Bauer Christoph C Fischer Kathleen K Austad Steven S Galliot Brigitte B
Development (Cambridge, England) 20200123 2
<i>Hydra</i> possesses three distinct stem cell populations that continuously self-renew and prevent aging in <i>Hydra vulgaris</i> However, sexual animals from the <i>H. oligactis</i> cold-sensitive strain <i>Ho_CS</i> develop an aging phenotype upon gametogenesis induction, initiated by the loss of interstitial stem cells. Animals stop regenerating, lose their active behaviors and die within 3 months. This phenotype is not observed in the cold-resistant strain <i>Ho_CR</i> To dissect the mecha ...[more]