Diverse and Flexible Transmission of fosA3 Associated with Heterogeneous Multidrug Resistance Regions in Salmonella enterica Serovar Typhimurium and Indiana Isolates.
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SUBMITTER: Fang LX
PROVIDER: S-EPMC6985750 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
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Diverse and Flexible Transmission of <i>fosA3</i> Associated with Heterogeneous Multidrug Resistance Regions in Salmonella enterica Serovar Typhimurium and Indiana Isolates.
Fang Liang-Xing LX Jiang Qi Q Deng Guo-Hui GH He Bing B Sun Ruan-Yang RY Zhang Jin-Fei JF Cen Dao-Ji DJ Miao Yuan-Yuan YY Wang Dong D Guo Wen-Ying WY Sun Jian J Liu Ya-Hong YH Liao Xiao-Ping XP
Antimicrobial agents and chemotherapy 20200127 2
We identified <i>fosA3</i> at a rate of 2.6% in 310 <i>Salmonella</i> isolates from food animals in Guangdong province, China. The <i>fosA3</i> gene was genetically linked to diverse antibiotic resistance genes (ARGs), including <i>mcr-1</i>, <i>bla</i><sub>CTX-M-14/55</sub>, <i>oqxAB</i>, and <i>rmtB</i> These gene combinations were embedded in heterogeneous <i>fosA3</i>-containing multidrug resistance regions on the transferable ST3-IncHI2 and F33:A-:B- plasmids and the chromosome. This indica ...[more]
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