Ontology highlight
ABSTRACT:
SUBMITTER: Eichler CE
PROVIDER: S-EPMC6986870 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Eichler Catherine E CE Hakes Anna C AC Hull Brooke B Gavis Elizabeth R ER
eLife 20200107
Partitioning of mRNAs into ribonucleoprotein (RNP) granules supports diverse regulatory programs within the crowded cytoplasm. At least two types of RNP granules populate the germ plasm, a cytoplasmic domain at the posterior of the <i>Drosophila</i> oocyte and embryo. Germ granules deliver mRNAs required for germline development to pole cells, the germ cell progenitors. A second type of RNP granule, here named founder granules, contains <i>oskar</i> mRNA, which encodes the germ plasm organizer. ...[more]