Functional and population genetic features of copy number variations in two dairy cattle populations.
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ABSTRACT:
SUBMITTER: Lee YL
PROVIDER: S-EPMC6988284 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Publications
Functional and population genetic features of copy number variations in two dairy cattle populations.
Lee Young-Lim YL Bosse Mirte M Mullaart Erik E Groenen Martien A M MAM Veerkamp Roel F RF Bouwman Aniek C AC
BMC genomics 20200128 1
<h4>Background</h4>Copy Number Variations (CNVs) are gain or loss of DNA segments that are known to play a role in shaping a wide range of phenotypes. In this study, we used two dairy cattle populations, Holstein Friesian and Jersey, to discover CNVs using the Illumina BovineHD Genotyping BeadChip aligned to the ARS-UCD1.2 assembly. The discovered CNVs were investigated for their functional impact and their population genetics features.<h4>Results</h4>We discovered 14,272 autosomal CNVs, which w ...[more]
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