Ontology highlight
ABSTRACT:
SUBMITTER: Cheng J
PROVIDER: S-EPMC6991642 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Cheng Jingliang J Peng Jiangzhou J Fu Jiewen J Khan Md Asaduzzaman MA Tan Pingping P Wei Chunli C Deng Xiyun X Chen Hanchun H Fu Junjiang J
Journal of cellular and molecular medicine 20191128 2
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer-related deaths in women worldwide. In this study, a large Chinese pedigree with breast cancer including a proband and two female patients was recruited and a familial history of breast cancer was collected by questionnaire. Clinicopathological assessments and neoadjuvant therapy-related information were obtained for the proband. Blood samples were taken, and gDNA was extracted. The BRCA1/2 and PALB2 genes were ...[more]