Cryo-electron tomography of bacteria: progress, challenges and future prospects.
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ABSTRACT:
SUBMITTER: Milne JL
PROVIDER: S-EPMC6993139 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Publications
Cryo-electron tomography of bacteria: progress, challenges and future prospects.
Milne Jacqueline L S JL Subramaniam Sriram S
Nature reviews. Microbiology 20090810 9
Recent advances in three-dimensional electron microscopy provide remarkable tools to image the interior of bacterial cells. Glimpses of cells at resolutions that are 1-2 orders of magnitude higher than those currently attained with light microscopy can now be obtained with cryo-electron tomography, especially when used in combination with new tools for image averaging. This Review highlights recent advances in this area and provides an assessment of the general applicability, current limitations ...[more]
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