Ontology highlight
ABSTRACT:
SUBMITTER: Wise MC
PROVIDER: S-EPMC6994112 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Wise Megan C MC Xu Ziyang Z Tello-Ruiz Edgar E Beck Charles C Trautz Aspen A Patel Ami A Elliott Sarah Tc ST Chokkalingam Neethu N Kim Sophie S Kerkau Melissa G MG Muthumani Kar K Jiang Jingjing J Fisher Paul D PD Ramos Stephany J SJ Smith Trevor Rf TR Mendoza Janess J Broderick Kate E KE Montefiori David C DC Ferrari Guido G Kulp Daniel W DW Humeau Laurent M LM Weiner David B DB
The Journal of clinical investigation 20200201 2
Interventions to prevent HIV-1 infection and alternative tools in HIV cure therapy remain pressing goals. Recently, numerous broadly neutralizing HIV-1 monoclonal antibodies (bNAbs) have been developed that possess the characteristics necessary for potential prophylactic or therapeutic approaches. However, formulation complexities, especially for multiantibody deliveries, long infusion times, and production issues could limit the use of these bNAbs when deployed, globally affecting their potenti ...[more]