Dataset Information

Cryptosporidium infecting wild cricetid rodents from the subfamilies Arvicolinae and Neotominae.

ABSTRACT: We undertook a study on Cryptosporidium spp. in wild cricetid rodents. Fecal samples were collected from meadow voles (Microtus pennsylvanicus), southern red-backed voles (Myodes gapperi), woodland voles (Microtus pinetorum), muskrats (Ondatra zibethicus) and Peromyscus spp. mice in North America, and from bank voles (Myodes glareolus) and common voles (Microtus arvalis) in Europe. Isolates were characterized by sequence and phylogenetic analyses of the small subunit ribosomal RNA (SSU) and actin genes. Overall, 33·2% (362/1089) of cricetids tested positive for Cryptosporidium, with a greater prevalence in cricetids from North America (50·7%; 302/596) than Europe (12·1%; 60/493). Principal Coordinate analysis separated SSU sequences into three major groups (G1-G3), each represented by sequences from North American and European cricetids. A maximum likelihood tree of SSU sequences had low bootstrap support and showed G1 to be more heterogeneous than G2 or G3. Actin and concatenated actin-SSU trees, which were better resolved and had higher bootstrap support than the SSU phylogeny, showed that closely related cricetid hosts in Europe and North America are infected with closely related Cryptosporidium genotypes. Cricetids were not major reservoirs of human pathogenic Cryptosporidium spp.

SUBMITTER: Stenger BLS

PROVIDER: S-EPMC6994186 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature

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Cryptosporidium infecting wild cricetid rodents from the subfamilies Arvicolinae and Neotominae.

Stenger Brianna L S BLS Horčičková Michaela M Clark Mark E ME Kváč Martin M Čondlová Šárka Š Khan Eakalak E Widmer Giovanni G Xiao Lihua L Giddings Catherine W CW Pennil Christopher C Stanko Michal M Sak Bohumil B McEvoy John M JM

Parasitology 20170905 3

We undertook a study on Cryptosporidium spp. in wild cricetid rodents. Fecal samples were collected from meadow voles (Microtus pennsylvanicus), southern red-backed voles (Myodes gapperi), woodland voles (Microtus pinetorum), muskrats (Ondatra zibethicus) and Peromyscus spp. mice in North America, and from bank voles (Myodes glareolus) and common voles (Microtus arvalis) in Europe. Isolates were characterized by sequence and phylogenetic analyses of the small subunit ribosomal RNA (SSU) and acti ...[more]

PMID: 28870264

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Dataset Information

Cryptosporidium infecting wild cricetid rodents from the subfamilies Arvicolinae and Neotominae.

Publications

Cryptosporidium infecting wild cricetid rodents from the subfamilies Arvicolinae and Neotominae.

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