Ontology highlight
ABSTRACT:
SUBMITTER: Yu L
PROVIDER: S-EPMC6994346 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Seminars in perinatology 20190801 1
Congenital diaphragmatic hernia (CDH) is a common birth defect that is associated with significant morbidity and mortality, especially when associated with additional congenital anomalies. Both environmental and genetic factors are thought to contribute to CDH. The genetic contributions to CDH are highly heterogeneous and incompletely defined. No one genetic cause accounts for more than 1-2% of CDH cases. In this review, we summarize the known genetic causes of CDH from chromosomal anomalies to ...[more]