Ontology highlight
ABSTRACT:
SUBMITTER: Lee ER
PROVIDER: S-EPMC6994664 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Lee Emma R ER Parkin Neil N Jennings Cheryl C Brumme Chanson J CJ Enns Eric E Casadellà Maria M Howison Mark M Coetzer Mia M Avila-Rios Santiago S Capina Rupert R Marinier Eric E Van Domselaar Gary G Noguera-Julian Marc M Kirkby Don D Knaggs Jeff J Harrigan Richard R Quiñones-Mateu Miguel M Paredes Roger R Kantor Rami R Sandstrom Paul P Ji Hezhao H
Scientific reports 20200131 1
Next generation sequencing (NGS) is a trending new standard for genotypic HIV-1 drug resistance (HIVDR) testing. Many NGS HIVDR data analysis pipelines have been independently developed, each with variable outputs and data management protocols. Standardization of such analytical methods and comparison of available pipelines are lacking, yet may impact subsequent HIVDR interpretation and other downstream applications. Here we compared the performance of five NGS HIVDR pipelines using proficiency ...[more]