Ontology highlight
ABSTRACT:
SUBMITTER: Irazoqui JE
PROVIDER: S-EPMC6995440 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Trends in immunology 20200117 2
Microphthalmia/TFE (MiT) transcription factors (TFs), such as transcription factor EB (TFEB) and transcription factor E3 (TFE3), are emerging as key regulators of innate immunity and inflammation. Rapid progress in the field requires a focused update on the latest advances. Recent studies show that TFEB and TFE3 function in innate immune cells to regulate antibacterial and antiviral responses downstream of phagocytosis, interferon (IFN)-γ, lipopolysaccharide (LPS), and adenosine receptors. Moreo ...[more]