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Eco-friendly approach to access of quinoxaline derivatives using nanostructured pyrophosphate Na2PdP2O7 as a new, efficient and reusable heterogeneous catalyst.

ABSTRACT: In the present study, we report the synthesis of various quinoxaline derivatives from direct condensation of substituted aromatic 1,2-diamine with 1,2-dicarbonyl catalyzed by nanostructured pyrophosphate Na2PdP2O7 as a new highly efficient bifunctionalheterogeneous catalyst. The quinoxaline synthesis was performed in ethanol as a green and suitable solvent at ambient temperature to afford the desired quinoxalines with good to excellent yields in shorter reaction times. Many Quinoxaline derivatives were successfully synthesized using various 1,2-diketones and 1,2-diamines at room temperature. Catalyst reusability showed that the Na2PdP2O7 catalyst exhibited excellent recyclability without significant loss in its catalytic activity after five consecutive cycles.

SUBMITTER: Danoun K

PROVIDER: S-EPMC6996184 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Eco-friendly approach to access of quinoxaline derivatives using nanostructured pyrophosphate Na2PdP2O7 as a new, efficient and reusable heterogeneous catalyst.

Dânoun Karim K Essamlali Younes Y Amadine Othmane O Mahi Hassan H Zahouily Mohamed M

BMC chemistry 20200203 1

In the present study, we report the synthesis of various quinoxaline derivatives from direct condensation of substituted aromatic 1,2-diamine with 1,2-dicarbonyl catalyzed by nanostructured pyrophosphate Na2PdP2O7 as a new highly efficient bifunctionalheterogeneous catalyst. The quinoxaline synthesis was performed in ethanol as a green and suitable solvent at ambient temperature to afford the desired quinoxalines with good to excellent yields in shorter reaction ...[more]

PMID: 32025664

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