Ontology highlight
ABSTRACT:
SUBMITTER: Rotwein P
PROVIDER: S-EPMC6996716 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Molecular and cellular endocrinology 20190311
Insulin-like growth factor 1 (IGF1) actions are essential for somatic growth and tissue repair. IGF1 gene regulation is controlled by many inputs, with growth hormone playing a major role. In most mammals, the 6-exon IGF1/Igf1 gene produces multiple transcripts via independent activity of its promoters plus alternative RNA splicing and differential polyadenylation. Here, by analyzing public genomic and RNA-sequencing repositories, I have characterized three Australian marsupial IGF1 genes. Koala ...[more]