Dataset Information

Lead and Arsenic in Shed Deciduous Teeth of Children Living Near a Lead-Acid Battery Smelter.

ABSTRACT: Lead (Pb) is a potent neurotoxicant with no safe level of exposure. Elevated levels of Pb and arsenic (As) are found in the air and soil near facilities that recycle lead-acid batteries in the United States. In urban Los Angeles County, California, a facility processed ?11 million batteries per year and operated for decades without proper environmental review. Measuring Pb and As in shed deciduous teeth is a promising technique to assess prenatal and early life exposure. In this pilot study coined the "Truth Fairy" Project, 50 shed deciduous teeth from 43 children living their entire lives within 2 miles of the smelter were analyzed to understand retrospective exposure to toxic metals using a community-driven research approach. Concentrations of Pb and As in teeth were assessed using laser-ablation-inductively coupled plasma-mass spectrometry. Soil Pb concentrations were determined using spatial kriging of surface soil measurements. The mean prenatal calcium normalized Pb levels in teeth samples (reported as a ratio 208Pb:43Ca) was 4.104 × 10-4 (SD 4.123 × 10-4), and the mean postnatal 208Pb:43Ca level was 4.109 × 10-4 (SD 3.369 × 10-4). Adjusted for maternal education and batch, we observe positive significant relationship between prenatal teeth Pb per 100 ppm increase in soil Pb (? = 3.48, 95% CI 1.11, 5.86). The Truth Fairy study suggests prenatal and early life exposure to toxic metals is associated with legacy soil contamination in an urban community near a smelter.

SUBMITTER: Johnston JE

PROVIDER: S-EPMC6996839 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Lead and Arsenic in Shed Deciduous Teeth of Children Living Near a Lead-Acid Battery Smelter.

Johnston Jill E JE Franklin Meredith M Roh Hannah H Austin Christine C Arora Manish M

Environmental science & technology 20190506 10

Lead (Pb) is a potent neurotoxicant with no safe level of exposure. Elevated levels of Pb and arsenic (As) are found in the air and soil near facilities that recycle lead-acid batteries in the United States. In urban Los Angeles County, California, a facility processed ∼11 million batteries per year and operated for decades without proper environmental review. Measuring Pb and As in shed deciduous teeth is a promising technique to assess prenatal and early life exposure. In this pilot study coin ...[more]

PMID: 31056909

Similar Datasets

Project description:Background:Lead can cause significant biological and neurologic damage, even at small concentrations, and young children are at higher risk. Informal recycling of lead batteries and lead-based workshops/industries have increased the burden of lead toxicity in developing countries, including India. Many informal recycling lead battery workshops have been established by the local people of Patna, Bihar as self-employment opportunities. However, most of the residents are not aware of the risk factors associated with lead poisoning. Objectives:The present pilot study aimed to assess blood lead levels (BLLs) and hemoglobin levels among children aged between 3 to 12 years in the settlement of Karmalichak near Patna, India. Materials and Methods:Children residing near the informal lead battery manufacturing unit were selected for BLL assessment. A total of 41 children were enrolled in the questionnairebased survey. Results:All the children in the present study had detectable lead concentrations in their blood. Only 9% of the studied children had a BLL ?5 ?g/dl, while 91% children had a BLL above >5 ?g/dl. Conclusions:The present study carried out in children of Karmalichak region of Patna, India was an attempt to better understand the problem of lead toxicity, describe the epidemiology of its adverse effects, identify sources and routes of exposure, illustrate the clinical effects and develop strategies of prevention so that remedial measures may be taken by government agencies and regulatory bodies. In view of the high lead levels in children in the study area, attempts are being made to develop strategies for future prevention by relocating the informal battery recycling workshops from the area. Moreover, parents have been advised to increase nutritional supplementation of children by providing calcium-, iron- and zinc-rich foods, including milk and vegetables. Participant Consent:Obtained. Ethical Approval:The study was approved by the ethical committee of Era's Lucknow Medical College & Hospital, Era University, Lucknow (India). Competing Interests:The authors declare no competing financial interests.

Project description:BackgroundLead, a potent neurotoxin, causes irreversible damage to the nervous system, and low- and middle-income countries face huge health and economic productivity losses due to childhood lead exposure. In Bangladesh, informal Used Lead Acid Battery (ULAB) recycling sites are an important source of lead pollution. Little is known about lead awareness among communities exposed to ULAB recycling. Therefore, this study aims to assess knowledge, attitudes, and practices related to lead pollution among caregivers of young children and adolescents living adjacent to informal ULAB sites.MethodsA cross-sectional study was conducted among 732 mothers of young children and adolescents in 4 districts of Bangladesh (survey and observation). Simple and multiple linear regression was conducted to describe patterns and predictors of lead-related knowledge and practices.Results60% of respondents had heard the name 'lead' ("shisha"). The mean knowledge score was low (19 out of 44). Residents of high-risk districts, male respondents, and those with more than 5 years of schooling were significantly more likely to have higher knowledge scores than others. In terms of attitude, 52% of respondents perceived lead to be risky for human health but 43% thought lead pollution was controllable. Observation of households for lead exposure revealed that 63% of children and adolescents play or pass by ULAB sites, 29% ate non-food items, 41% of households had visible paint chips on the walls, 59% households used polished turmeric and 15% used lead-soldered cans to store foods. Among protective practices, 70% reported cleaning floors, 84% consumed iron-rich foods, and 48% consumed calcium-rich foods.ConclusionsThe population had a high potential for lead exposure. Their knowledge about lead was limited, and risk perception was moderate. To reduce lead exposure and increase knowledge and awareness among the at-risk population, it is crucial to take measures such as mass awareness campaigns through media and schools. It is important to strengthen the implementation of existing policies, such as policies on leaded gasoline, paints, and lead-acid batteries, that can address the sources of lead exposure for the community.

Dataset Information

Lead and Arsenic in Shed Deciduous Teeth of Children Living Near a Lead-Acid Battery Smelter.

Publications

Lead and Arsenic in Shed Deciduous Teeth of Children Living Near a Lead-Acid Battery Smelter.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets