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Primary Nasal Epithelial Cells From Allergic and Non-allergic Individuals Show Comparable Barrier Function.


ABSTRACT: Previous reports suggested that ex vivo cultured primary nasal epithelial cells from allergic patients differ from those from non-allergic individuals by genuinely reduced barrier function. By contrast, we found that primary nasal epithelial cells from allergic and non-allergic individuals showed comparable barrier function and secretion of cytokines.

SUBMITTER: Waltl EE 

PROVIDER: S-EPMC6997283 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Primary Nasal Epithelial Cells From Allergic and Non-allergic Individuals Show Comparable Barrier Function.

Waltl Eva E EE   Stanek Victoria V   Mueller Christian A CA   Kiss Renata R   Eckl-Dorna Julia J   Valenta Rudolf R   Niederberger Verena V  

Allergy, asthma & immunology research 20200301 2


Previous reports suggested that ex vivo cultured primary nasal epithelial cells from allergic patients differ from those from non-allergic individuals by genuinely reduced barrier function. By contrast, we found that primary nasal epithelial cells from allergic and non-allergic individuals showed comparable barrier function and secretion of cytokines. ...[more]

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