Ontology highlight
ABSTRACT:
SUBMITTER: Tanaka H
PROVIDER: S-EPMC6997454 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Tanaka Hiroshi H Nakayama Tomomichi T Tsukamoto Michiko M Watanabe Akihide A Nakamura Takahiro T Yokoi Norihiko N Sotozono Chie C Kinoshita Shigeru S
Scientific reports 20200203 1
Nasolacrimal duct obstruction (NLDO) is thought to be due to inflammation and fibrosis of lacrimal duct epithelial cells (LDECs). Here we investigated the effect of rebamipide, a drug that is used for the protection of the mucosa and the treatment of gastritis and gastroduodenal ulcers, on LDECs, both in vitro and in vivo. In this study, LDECs were cultured from rabbit lacrimal duct tissues, and the barrier function of LEDCs was examined in vitro via transepithelial electrical resistance (TER) m ...[more]