Ontology highlight
ABSTRACT:
SUBMITTER: Xiang D
PROVIDER: S-EPMC6997547 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Xiang Dongfang D Wu Xin X Cao Wei W Xue Bin B Qin Meng M Cao Yi Y Wang Wei W
Frontiers in chemistry 20200128
Hydrogels with photo-responsive mechanical properties have found broad biomedical applications, including delivering bioactive molecules, cell culture, biosensing, and tissue engineering. Here, using a photocleavable protein, PhoCl, as the crosslinker we engineer two types of poly(ethylene glycol) hydrogels whose mechanical stability can be weakened or strengthened, respectively, upon visible light illumination. In the photo weakening hydrogels, photocleavage leads to rupture of the protein cros ...[more]