Dataset Information

Contamination Profiles of Perfluoroalkyl Substances (PFAS) in Groundwater in the Alluvial-Pluvial Plain of Hutuo River, China.

ABSTRACT: Over the past decade, concerns about perfluoroalkyl substances (PFAS) have increased rapidly among the scientific community due to their global distribution and persistence in various environmental matrices. The occurrences of 10 PFAS in groundwater in the alluvial-pluvial plain of Hutuo River (APPHR) in the North China Plain (NCP) were analyzed via UPLC-MS/MS and solid phase extraction. Total PFAS concentrations ranged from 0.56 ng/L to 13.34 ng/L, with an average value of 2.35 ng/L. Perfluorooctanoic acid (PFOA) and perfluorohexanoic acid (PFHxA) were dominant PFAS contaminants with high detection rates of 98.39% and 95.16%, respectively, and PFOA was the main pollutant with a mean concentration of 0.65 ng/L. The hydrogeological conditions have an important influence on the concentrations of PFAS in groundwater. Comparatively, the concentration of PFAS in groundwater in the study area is not very high, but it reflects that the groundwater in this region is affected by industrial sources to some extent. Local government should pay more attention on industrial pollution control and groundwater protection in this area.

SUBMITTER: Liu Y

PROVIDER: S-EPMC6997942 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Contamination Profiles of Perfluoroalkyl Substances (PFAS) in Groundwater in the Alluvial-Pluvial Plain of Hutuo River, China.

Liu Yan Y Li Xue X Wang Xing X Qiao Xiaocui X Hao Shuran S Lu Jingrang J Duan Xiaodi X Dionysiou Dionysios D DD Zheng Binghui B

Water 20191101 11

Over the past decade, concerns about perfluoroalkyl substances (PFAS) have increased rapidly among the scientific community due to their global distribution and persistence in various environmental matrices. The occurrences of 10 PFAS in groundwater in the alluvial-pluvial plain of Hutuo River (APPHR) in the North China Plain (NCP) were analyzed via UPLC-MS/MS and solid phase extraction. Total PFAS concentrations ranged from 0.56 ng/L to 13.34 ng/L, with an average value of 2.35 ng/L. Perfluoroo ...[more]

PMID: 32021704

Similar Datasets

Project description:BackgroundEnvironmental exposures to industrial chemicals, including perfluoroalkyl substances (PFAS), may play a role in bone development and future risk of osteoporosis. However, as prospective evidence is limited, the role of developmental PFAS exposures in bone density changes in childhood is unclear. The objective of this study was to estimate associations between serum-PFAS concentrations measured in infancy and early childhood and areal bone mineral density (aBMD) measured at age 9 years in a birth cohort of children from the Faroe Islands.MethodsWe prospectively measured concentrations of five PFAS in cord serum and serum collected at 18 months, 5 years and 9 years, and conducted whole-body DXA scans at the 9-year clinical visit. Our study included 366 mother-child pairs with DXA scans and at least one PFAS measurement. We estimated covariate-adjusted associations of individual PFAS concentrations with age-, sex- and height-adjusted aBMD z-scores using multivariable regression models and applied formal mediation analysis to estimate the possible impact of by several measures of body composition. We also evaluated whether associations were modified by child sex.ResultsWe found PFAS exposures in childhood to be negatively associated with aBMD z-scores, with the strongest association seen for perfluorononanoic acid (PFNA) at age 5 years. A doubling in age-5 PFNA was associated with a 0.15 decrease in aBMD z-score (95% CI: - 0.26, - 0.039). The PFNA-aBMD association was significantly stronger in males than females, although effect modification by sex was not significant for other PFAS exposures. Results from the mediation analysis suggested that any potential associations between aBMD and 18-month PFAS concentrations may be mediated by total body fat and BMI, although most estimated total effects for PFAS exposures at age 18 months were non-significant. PFAS exposures at age 9 were not associated with age-9 aBMD z-scores.ConclusionsThe PFAS-aBMD associations identified in this and previous studies suggest that bone may be a target tissue for PFAS. Pediatric bone density has been demonstrated to strongly track through young adulthood and possibly beyond; therefore, these prospective results may have important public health implications.

Dataset Information

Contamination Profiles of Perfluoroalkyl Substances (PFAS) in Groundwater in the Alluvial-Pluvial Plain of Hutuo River, China.

Publications

Contamination Profiles of Perfluoroalkyl Substances (PFAS) in Groundwater in the Alluvial-Pluvial Plain of Hutuo River, China.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets