Changes in microbiome and metabolomic profiles of fecal samples stored with stabilizing solution at room temperature: a pilot study.

ABSTRACT: The gut microbiome is related to various host health conditions through metabolites produced by microbiota. Investigating their relationships involves association analysis of the population-level microbiome and metabolome data, which requires the appropriate collection, handling, and storage of specimens. Simplification of the specimen handling processes will facilitate such investigations. As a pilot study for population-level studies, we collected the fecal samples from three volunteers and tested whether a single sample collection procedure, particularly using OMNIgene-GUT, can be used to reliably obtain both microbiome and metabolome data. We collected fecal samples from three young and healthy Korean adults, stored them at room temperature with and without OMNIgene-GUT solution up to

SUBMITTER: Lim MY 

PROVIDER: S-EPMC7000387 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature