Ontology highlight
ABSTRACT:
SUBMITTER: Meadows V
PROVIDER: S-EPMC7000431 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Meadows Vik V Kennedy Lindsey L Kundu Debjyoti D Alpini Gianfranco G Francis Heather H
Frontiers in medicine 20200129
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases. The discovery of important bile acid signaling mechanisms, as well as their role in metabolism, has increased the interest in bile acid/bile acid receptor research development. Bile acid levels and speciation are dysregulated during liver injury/damage resulting in ...[more]