Ontology highlight
ABSTRACT:
SUBMITTER: Brcic L
PROVIDER: S-EPMC7000742 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Brčić Luka L Barić Ana A Benzon Benjamin B Brekalo Marko M Gračan Sanda S Kaličanin Dean D Škrabić Veselin V Zemunik Tatijana T Barbalić Maja M Novak Ivana I Pešutić Pisac Valdi V Punda Ante A Boraska Perica Vesna V
Scientific reports 20200204 1
Thyroid volume of Hashimoto's thyroiditis (HT) patients varies in size over the course of disease and it may reflect changes in biological function of thyroid gland. Patients with subclinical hypothyroidism predominantly have increased thyroid volume whereas patients with more pronounced hypothyroidism have smaller thyroid volumes. Suggested mechanism for thyroid atrophy is thyrocyte death due to apoptosis. We performed the first genome-wide association study (GWAS) of thyroid volume in two grou ...[more]