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Non-alcoholic fatty liver disease in lean individuals.

ABSTRACT: Non-alcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease, encompassing a spectrum from non-alcoholic fatty liver to non-alcoholic steatohepatitis, which can progress to cirrhosis. It has recently been recognised that NAFLD also occurs in individuals who are not obese, especially in Asian populations. In these patients, NAFLD manifests at lower overall body mass index thresholds in the presence of increased visceral adipose tissue. Currently, the principles of clinical management are similar to those in obese individuals, although, in specific regions and clinical situations, unique aetiologies of NAFLD must be treated specifically.

SUBMITTER: Albhaisi S

PROVIDER: S-EPMC7001558 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

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Non-alcoholic fatty liver disease in lean individuals.

Albhaisi Somaya S Chowdhury Abhijit A Sanyal Arun J AJ

JHEP reports : innovation in hepatology 20190830 4

Non-alcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease, encompassing a spectrum from non-alcoholic fatty liver to non-alcoholic steatohepatitis, which can progress to cirrhosis. It has recently been recognised that NAFLD also occurs in individuals who are not obese, especially in Asian populations. In these patients, NAFLD manifests at lower overall body mass index thresholds in the presence of increased visceral adipose tissue. Currently, the principles of clinical ...[more]

PMID: 32039383

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